Chromatin Biology and
Genome Regulation
Each one of us began life as a single cell. We study how the genetic information carried in that single cell is used to generate the hundreds of different kinds of cells that make us human.
Image by Yifan Xu. Deposition of H3.3 (green spheres) is controlled by distinct factors at specific genomic regions. At genes and regulatory elements (right), the histone chaperone Hira (man in red jacket) controls H3.3 localization. At repeat regions (left), the histone chaperone Daxx (man in white jacket) controls deposition of H3.3.
